IFOM, Research Programs
The research programs running at IFOM are focused on basic and applied molecular oncology. Scientists at IFOM study the fundamental biological mechanisms involving DNA and proteins that are responsible for the development of cancer. Their aim is to identify “key” processes that can be disrupted or stimulated by therapeutic intervention. The scientists and Principal Investigators working at IFOM are selected according to rigorous international evaluation criteria.
The 19 research programs at IFOM cover a wide range of topics including the molecular genetics of cancer, tumor angiogenesis, the genetics of metastasis, mechanisms of cellular aging, intracellular signal transduction, proteomics, and cellular and ultrastructural oncology.
These research programs are relevant both to basic research and to translational/applied research. Their final goal is to produce results that can be rapidly translated into diagnostic and therapeutic tools.
Although the majority of the research programs are being conducted at IFOM in Milan, some programs are based at external institutions, including the University of Genoa and the Institute for Cancer Research and Treatment (IRCC) of Candiolo (Turin).
Detailed description of the research programs for sector experts. (link to the IFOM-IEO Campus web site)
Alberto BardelliMutational and functional profiling of cancer alleles
Francesco BlasiTranscriptional mechanisms in development and tumor formation
Dana BranzeiDNA Repair
Giovanni BonioloBiomedical humanities and epistemology
Stefano CasolaMolecular mechanisms of peripheral B cell development and lymphomagenesis
Ugo CavallaroCell adhesion and signalling in tumor progression and angiogenesis
Andrea CilibertoComputational Cell Biology
Fabrizio d'Adda di FagagnaTelomeres and cellular senescence
Elisabetta DejanaNew strategies to inhibit tumor angiogenesis
Alberto DiasproMicroscopy and Nanoscopy for 3D tracking and visualization of biological molcules in cellular systems by means of linear and non-linear optical interactions
Pier Paolo Di FioreEndocytosis, Signalling and Cancer
Marco FoianiGenome integrity
Marina MioneGenetic of cancer and tumor angiogenesis in zebrafish
Paolo RadiceMolecular Genetics of Cancer
Simona PoloLa monoubiquitinazione come regolazione funzionale delle proteine
Giorgio ScitaSignaling regulating acting dynamics in cell motility
Nicolai SideniusCell matrix signaling
Carlo TacchettiIFOM Centre of Cell Oncology and Ultrastructure
Thomas VaccariRegulation of Tumor Suppression by Endocytosis in Drosophila

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