IFOM Publications 2008

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Activity Report IFOM 2008

AAntoniou AC, Spurdle AB, Sinilnikova OM, Healey S, Pooley KA, Schmutzler RK, Versmold B, Engel C, Meindl A, Arnold N, Hofmann W, Sutter C, Niederacher D, Deissler H, Caldes T, Kämpjärvi K, Nevanlinna H, Simard J, Beesley J, Chen X; Kathleen Cuningham Consortium for Research into Familial Breast Cancer, Neuhausen SL, Rebbeck TR, Wagner T, Lynch HT, Isaacs C, Weitzel J, Ganz PA, Daly MB, Tomlinson G, Olopade OI, Blum JL, Couch FJ, Peterlongo P, Manoukian S, Barile M, Radice P, Szabo CI, Pereira LH, Greene MH, Rennert G, Lejbkowicz F, Barnett-Griness O, Andrulis IL, Ozcelik H; OCGN, Gerdes AM, Caligo MA, Laitman Y, Kaufman B, Milgrom R, Friedman E; Swedish BRCA1 and BRCA2 study collaborators, Domchek SM, Nathanson KL, Osorio A, Llort G, Milne RL, Benítez J, Hamann U, Hogervorst FB, Manders P, Ligtenberg MJ, van den Ouweland AM; DNA-HEBON collaborators, Peock S, Cook M, Platte R, Evans DG, Eeles R, Pichert G, Chu C, Eccles D, Davidson R, Douglas F; EMBRACE, Godwin AK, Barjhoux L, Mazoyer S, Sobol H, Bourdon V, Eisinger F, Chompret A, Capoulade C, Bressac-de Paillerets B, Lenoir GM, Gauthier-Villars M, Houdayer C, Stoppa-Lyonnet D; GEMO, Chenevix-Trench G, Easton DF; CIMBA.
Common Breast Cancer-Predisposition Alleles Are Associated with Breast Cancer Risk in BRCA1 and BRCA2 Mutation Carriers.
Am J Hum Genet. 2008, Apr;82(4); 937-48. IF: 11,092
Marroni F, Cipollini G, Peissel B, D'Andrea E, Pensabene M, Radice P, Caligo MA, Presciuttini S, Bevilacqua G.
Reconstructing the Genealogy of a BRCA1 Founder Mutation by Phylogenetic Analysis.
Ann Hum Genet. 2008, May, 72(Pt 3); 310-8. IF: 2,307
Sahores M, Prinetti A, Chiabrando G, Blasi F, Sonnino S.
uPA binding increases UPAR localization to lipid rafts and modifies the receptor microdomain composition.
Biochim Biophys Acta. 2008, Jan;1778(1); 250-259. NO IF
Ami D, Neri T, Natalello A, Mereghetti P, Doglia SM, Zanoni M, Zuccotti M, Garagna S, Redi CA.
Embryonic stem cell differentiation studied by FT-IR spectroscopy.
Biochim Biophys Acta, 2008, Jan;1783(1); 98-106. NO IF
Cesaroni M, Cittaro D, Brozzi A, Pelicci PG, Luzi L.
CARPET: a web-based package for the analysis of ChIP-chip and expression tiling data.
Bioinformatics. 2008, Dec 15;24(24); 2918-20 . IF: 5,039
Cermenati S, Moleri S, Cimbro S, Corti P, Del Giacco L, Amodeo R, Dejana E, Koopman P, Cotelli F, Beltrame M.
Sox18 and Sox7 play redundant roles in vascular development.
Blood. 2008, Mar 1;111(5); 2657-66. IF: 10,896
Birdsey GM, Dryden NH, Amsellem V, Gebhardt F, Sahnan K, Haskard DO, Dejana E, Mason JC, Randi AM.
Transcription factor Erg regulates angiogenesis and endothelial apoptosis through VE-cadherin.
Blood. 2008, Apr 1;111(7); 3498-506. IF: 10,896
Alfano M, Mariani SA, Elia C, Pardi R, Blasi F, Poli G.
Ligand-engaged urokinase-type plasminogen activator receptor (uPAR) and activation of the CD11b/CD18 (Mac1) integrin inhibit late events of HIV expression in monocytic cells.
Blood. Epub 2008 Oct 21. IF: 10,896
Mosca R, Brannetti B, Schneider TR.
Alignment of protein structures in the presence of domain motions.
BMC Bioinformatics. 2008, Aug 27;9; 352. IF: 3,493
Loi S, Haibe-Kains B, Desmedt C, Wirapati P, Lallemand F, Tutt AM, Gillet C, Ellis P, Ryder K, Reid JF, Daidone MG, Pierotti MA, Berns EM, Jansen MP, Foekens JA, Delorenzi M, Bontempi G, Piccart MJ, Sotiriou C.
Predicting prognosis using molecular profiling in estrogen receptor-positive breast cancer treated with tamoxifen.
BMC Genomics. 2008, May 22;9; 239. IF: 4,180
De Vecchi G, Verderio P, Pizzamiglio S, Manoukian S, Barile M, Fortuzzi S, Ravagnani F, Pierotti MA, Radice P, Peterlongo P.
Evidences for association of the CASP8 -652 6N del promoter polymorphism with age at diagnosis in familial breast cancer cases.
Breast Cancer Res Treat. 2009 Feb;113(3); 607-8 (Epub 2008 Mar 16). IF: 4,453
Antoniou AC, Cunningham AP, Peto J, Evans DG, Lalloo F, Narod SA, Risch HA, Eyfjord JE, Hopper JL, Southey MC, Olsson H, Johannsson O, Borg A, Pasini B, Radice P, Manoukian S, Eccles DM, Tang N, Olah E, Anton-Culver H, Warner E, Lubinski J, Gronwald J, Gorski B, Tryggvadottir L, Syrjakoski K, Kallioniemi OP, Eerola H, Nevanlinna H, Pharoah PD, Easton DF.
The BOADICEA model of genetic susceptibility to breast and ovarian cancers: updates and extensions.
Br J Cancer. 2008, Apr 22;98(8);1457-66. IF: 4,365
Osorio A, Pollán M, Pita G, Schmutzler RK, Versmold B, Engel C, Meindl A, Arnold N, Preisler-Adams S, Niederacher D, Hofmann W, Gadzicki D, Jakubowska A, Hamann U, Lubinski J, Toloczko-Grabarek A, Cybulski C, Debniak T, Llort G, Yannoukakos D, Díez O, Peissel B, Peterlongo P, Radice P, Heikkinen T, Nevanlinna H, Mai PL, Loud JT, McGuffog L, Antoniou AC, Benitez J.
An evaluation of the polymorphisms Ins16bp and Arg72Pro in p53 as breast cancer risk modifiers in BRCA1 and BRCA2 mutation carriers.
Br J Cancer. 2008, Sep 16;99(6); 974-7. IF: 4,365
Liedtke C, Cardone L, Tordai A, Yan K, Gomez HL, Figureoa LJ, Hubbard RE, Valero V, Souchon EA, Symmans WF, Hortobagyi GN, Bardelli A, Pusztai L
PIK3CA-activating mutations and chemotherapy sensitivity in stage II-III breast cancer.
Breast Cancer Res. 2008, 10(2); R27. IF: 4,371
De Vecchi G, Verderio P, Pizzamiglio S, Manoukian S, Bernard L, Pensotti V, Volorio S, Ravagnani F, Radice P, Peterlongo P.
The p53 Arg72Pro and Ins16bp polymorphisms and their haplotypes are not associated with breast cancer risk in BRCA-mutation negative familial cases.
Cancer Detect Prev. 2008, 32(2); 140-3 . IF: 1,600
Tapinassi C, Gerbino E, Malazzi O, Micucci C, Gasparini P, Najera MJ, Calasanz MJ, Odero MD, Pelicci PG, Belloni E.
A new dic(7;12)(p12.21;p12.2) chromosome aberration in a case of acute myeloid leukemia.
Cancer Genet Cytogenet. 2008, Sep;185(2); 102-5. IF: 1,559
Fernandez LC, Errico MC, Bottero L, Penkov D, Resnati M, Blasi F, Caré A.
Oncogenic HoxB7 requires TALE cofactors and is inactivated by a dominant-negative Pbx1 mutant in a cell-specific manner.
Cancer Lett. 2008, Aug 8;266(2); 44-55. IF: 3,398
Frattini M, Gallino G, Signoroni S, Balestra D, Lusa L, Battaglia L, Sozzi G, Bertario L, Leo E, Pilotti S, Pierotti MA.
Quantitative and qualitative characterization of plasma DNA identifies primary and recurrent colorectal cancer.
Cancer Lett. 2008, May 18;263 (2); 70-81. IF: 3,398
Zecchini S., Bianchi M., Colombo N., Fasani R., Goisis, G., Casadio C., Viale G., Liu J., Herlyn M., Godwin A.K., Nuciforo P., and Cavallaro U.
The differential role of L1 in ovarian carcinoma and normal ovarian surface epithelium.
Cancer Res. 2008, Feb 15;68(4); 1110-8. IF: 7,672
Ciferri C, Pasqualato S, Screpanti E, Varetti G, Santaguida S, Dos Reis G, Maiolica A, Polka J, De Luca JG, De Wulf P, Salek M, Rappsilber J, Moores CA, Salmon ED, Musacchio A.
Implications for kinetochore-microtubule attachment from the structure of an engineered Ndc80 complex.
Cell. 2008, May 2;133(3); 427-39. IF: 29,887
Palamidessi A, Frittoli E, Garré M, Faretta M, Mione M, Testa I, Diaspro A, Lanzetti L, Scita G, Di Fiore PP.
Endocytic trafficking of rac is required for the spatial restriction of signaling in cell migration.
Cell. 2008, Jul 11;134(1); 135-47. IF: 29,887
Acosta JC, O'Loghlen A, Banito A, Guijarro MV, Augert A, Raguz S, Fumagalli M, Da Costa M, Brown C, Popov N, Takatsu Y, Melamed J, d'Adda di Fagagna F, Bernard D, Hernando E, Gil J.
Chemokine signaling via the CXCR2 receptor reinforces senescence.
Cell. 2008, Jun 13;133(6); 1006-18. IF: 29,887
Polo S, Di Fiore PP.
Finding the Right Partner: Science or ART?
Cell. 2008, Nov 14;135(4); 590-2. IF: 29,887
Bianchi F, Nicassio F, Di Fiore PP.
Unbiased vs. biased approaches to the identification of cancer signatures: the case of lung cancer.
Cell Cycle. 2008, Jan 14;7(6). IF: 3,314
Arena S, Bardelli A.
Understanding how kinase-targeted therapies work.
Cell Cycle. 2008, Jun;7(11); 1560-3. IF: 3,314
Fiorani S, Mimun G, Caleca L, Piccini D, Pellicioli A.
Characterization of the activation domain of the Rad53 checkpoint kinase.
Cell Cycle. 2008, Feb 15;7(4); 493-9. IF: 3,314
Di Micco R, Cicalese A, Fumagalli M, Dobreva M, Verrecchia A, Pelicci PG, di Fagagna FD.
DNA damage response activation in mouse embryonic fibroblasts undergoing replicative senescence and following spontaneous immortalization.
Cell Cycle. 2008, 8;7(22). IF: 3,314
Vissers JH, Nicassio F, van Lohuizen M, Di Fiore PP, Citterio E.
The many faces of ubiquitinated histone H2A: insights from the DUBs.
Cell Div. 2008, Apr 22;3(1):8. NO IF
Zovein AC, Hofmann JJ, Lynch M, French WJ, Turlo KA, Yang Y, Becker MS, Zanetta L, Dejana E, Gasson JC, Tallquist MD, Iruela-Arispe ML.
Fate tracing reveals the endothelial origin of hematopoietic stem cells.
Cell Stem Cell. 2008, Dec 4;3(6); 625-36. NO IF
Mezzanzanica D, Fabbi M, Bagnoli M, Staurengo S, Losa M, Balladore E, Alberti P, Lusa L, Ditto A, Ferrini S, Pierotti MA, Barbareschi M, Pilotti S, Canevari S.
Subcellular Localization of Activated Leukocyte Cell Adhesion Molecule Is a Molecular Predictor of Survival in Ovarian Carcinoma Patients.
Clin Cancer Res. 2008, Mar 15;14(6); 1726-1733. IF: 6,250
Rudini N, Dejana E.
Adherens junctions.
Curr Biol. 2008, Dec 9;18(23); R1080-2. IF: 10,539
Disanza A, Scita G.
Cytoskeletal regulation: coordinating actin and microtubule dynamics in membrane trafficking.
Curr Biol. 2008, Sep 23;18(18); R873-5. IF: 10,539
Pocock R, Mione M, Hussain S, Maxwell S, Pontecorvi M, Aslam S, Gerrelli D, Sowden JC, Woollard A.
Neuronal function of Tbx20 conserved from nematodes to vertebrates.
Dev Biol. 2008, May 15;317(2); 671-85. IF: 4,714
Combes AN, Wilhelm D, Davidson T, Dejana E, Harley V, Sinclair A, Koopman P.
Endothelial cell migration directs testis cord formation.
Dev Biol. 2009, Feb 1;326(1); 112-120 (Epub 2008 Nov 7.) IF: 4,714
Sigismund S, Argenzio E, Tosoni D, Cavallaro E, Polo S, Di Fiore PP.
Clathrin-mediated internalization is essential for sustained EGFR signaling but dispensable for degradation.
Dev Cell. 2008, Aug;15(2); 209-19. IF:12,436
Mione M, Baldessari D, Deflorian G, Nappo G, Santoriello C
How neuronal migration contributes to the morphogenesis of the CNS: insights from the zebrafish.
Dev Neurosci. 2008, 30(1-3); 65-81. NO IF
Gore AV, Lampugnani MG, Dye L, Dejana E, Weinstein BM.
Combinatorial interaction between CCM pathway genes precipitates hemorrhagic stroke.
Dis Model Mech. 2008, Nov;1(4-5); 275-81. NO IF
Muzzini DM, Plevani P, Boulton SJ, Cassata G, Marini F.
Caenorhabditis elegans POLQ-1 and HEL-308 function in two distinct DNA interstrand cross-link repair pathways.
DNA Repair (Amst). 2008, Jun 1;7(6); 941-50. IF: 4,018
Ohuchi T, Seki M, Branzei D, Maeda D, Ui A, Ogiwara H, Tada S, Enomoto T.
Rad52 sumoylation and its involvement in the efficient induction of homologous recombination.
DNA Repair (Amst). 2008, Jun 1;7(6); 879-89. IF: 4,018
Rudini N, Felici A, Giampietro C, Lampugnani M, Corada M, Swirsding K, Garrè M, Liebner S, Letarte M, Ten Dijke P, Dejana E.
VE-cadherin is a critical endothelial regulator of TGF-beta signalling.
EMBO J. 2008, Apr 9;27(7); 993-1004. IF: 8,662
Nyqvist D, Giampietro C, Dejana E.
Deciphering the functional role of endothelial junctions by using in vivo models.
EMBO Rep. 2008, Aug;9(8); 742-7. IF: 7,450
Cappelletti V, Gariboldi M, De Cecco L, Toffanin S, Reid JF, Lusa L, Bajetta E, Celio L, Greco M, Fabbri A, Pierotti MA, Daidone MG.
Patterns and changes in gene expression following neo-adjuvant anti-estrogen treatment in estrogen receptor-positive breast cancer.
Endocr Relat Cancer. 2008, Jun;15(2); 439-449. IF: 5,193
Martin-Padura I, de Nigris F, Migliaccio E, Mansueto G, Minardi S, Rienzo M, Lerman LO, Stendardo M, Giorgio M, De Rosa G, Pelicci PG, Napoli C.
p66(Shc) Deletion Confers Vascular Protection in Advanced Atherosclerosis in Hypercholesterolemic Apolipoprotein E Knockout Mice.
Endothelium. 2008, Sep-Oct;15(5); 276-87. IF: 1,74
Testa I, Garrè M, Parazzoli D, Barozzi S, Ponzanelli I, Mazza D, Faretta M, Diaspro A.
Photoactivation of pa-GFP in 3D: optical tools for spatial confinement.
Eur Biophys J. 2008, Apr;230(Pt 1); 48-60. IF: 2,238
Tavecchio M, Simone M, Erba E, Chiolo I, Liberi G, Foiani M, D'Incalci M, Damia G.
Role of homologous recombination in trabectedin-induced DNA damage.
Eur J Cancer. 2008, Mar;44(4); 609-18. IF: 4,454
Madsen CD, Sidenius N.
The interaction between urokinase receptor and vitronectin in cell adhesion and signaling
Eur J Cell Biol. 2008, Sep;87(8-9); 617-29. IF: 3,224
d'Adda di Fagagna F.
Cellular senescence and cellular longevity: nearly 50 years on and still working on it.
Experimental Cell research. 2008, Jun 10;314(9); 1907-8. IF: 3,695
Tosoni D, Cestra G.
CAP (Cbl associated protein) regulates receptor-mediated endocytosis.
FEBS Lett. 2009, Jan 22;583(2); 293-300 (Epub 2008 Dec 29). IF: 3,263
Vetrano S, Rescigno M, Cera MR, Correale C, Rumio C, Doni A, Fantini M, Sturm A, Borroni E, Repici A, Locati M, Malesci A, Dejana E, Danese S.
Unique Role of Junctional Adhesion Molecule-A in Maintaining Mucosal Homeostasis in Inflammatory Bowel Disease.
Gastroenterology. 2008, Jul;135(1); 173-84. IF: 11,673
Bermejo R, Branzei D, Foiani M.
Cohesion by topology: sister chromatids interlocked by DNA.
Genes Dev. 2008, Sep 1;22(17); 2297-301. IF: 14,795
Settembre C, Fraldi A, Jahreiss L, Spampanato C, Venturi C, Medina D, Pablo RD, Tacchetti C, Rubinsztein DC, Ballabio A.
A Block of Autophagy in Lysosomal Storage Disorders.
Hum Mol Genet. 2008, Jan 1;17(1); 119-29. IF: 7,806
Benvenuti S, Frattini M, Arena S, Zanon C, Cappelletti V, Coradini D, Daidone MG, Pilotti S, Pierotti MA, Bardelli A.
PIK3CA cancer mutations display gender and tissue specificity patterns.
Hum Mutat. 2008, Feb;29(2); 284-8. IF: 6,273
Spurdle AB, Couch FJ, Hogervorst FB, Radice P, Sinilnikova OM; IARC Unclassified Genetic Variants Working Group.
Prediction and assessment of splicing alterations: implications for clinical testing
Hum Mutat. 2008, Nov;29(11); 1304-13. IF: 6,273
Bleeker FE, Lamba S, Rodolfo M, Scarpa A, Leenstra S, Vandertop WP, Bardelli A.
Mutational profiling of cancer candidate genes in glioblastoma, melanoma and pancreatic carcinoma reveals a snapshot of their genomic landscapes.
Hum Mutat. 2009, Feb;30(2); E451-9.( Epub 2008 Dec 4.) IF: 6,273
Hao Z, Duncan GS, Seagal J, Su YW, Hong C, Haight J, Chen NJ, Elia A, Wakeham A, Li WY, Liepa J, Wood GA, Casola S, Rajewsky K, Mak TW.
Fas Receptor Expression in Germinal-Center B Cells Is Essential for T and B Lymphocyte Homeostasis.
Immunity. 2008, Oct;29(4); 615-27. IF: 19,266
Pelizzoli R, Tacchetti C, Luzzi P, Strangio A, Bellese G, Zappia E, Guazzi S.
TTF-1/NKX2.1 up-regulates the in vivo transcription of nestin.
Int J Dev Biol. 2008, 52(1); 55-62. IF: 2,830
Toffanin S, Daidone MG, Miodini P, De Cecco L, Gandellini P, Cappelletti V.
Clusterin: A potential target for improving response to antiestrogens.
Int J Oncol. 2008, Oct;33(4); 791-8. IF: 2,295
Malengo G, Andolfo A, Sidenius N, Gratton E, Zamai M, Caiolfa VR.
Fluorescence correlation spectroscopy and photon counting histogram on membrane proteins: functional dynamics of the glycosylphosphatidylinositol-anchored urokinase plasminogen activator receptor.
J Biomed Opt. 2008, May-Jun;13(3); 31215. IF: 3,084
Bianchini P, Calzia D, Ravera S, Candiano G, Bachi A, Morelli A, Bruschi M, Pepe IM, Diaspro A, Panfoli I.
Live imaging of mammalian retina: rod outer segments are stained by conventional mitochondrial dyes.
J Biomed Opt. 2008, Sep-Oct;13(5). IF: 3,084
Di Fiore PP
Playing both sides: nucleophosmin between tumor suppression and oncogenesis.
J Cell Biol. 2008, Jul 14;182(1); 7-9. IF: 9,598
Liebner S, Corada M, Bangsow T, Babbage J, Taddei A, Czupalla CJ, Reis M, Felici A, Wolburg H, Fruttiger M, Taketo MM, von Melchner H, Plate KH, Gerhardt H, Dejana E.
Wnt/beta-catenin signaling controls development of the blood-brain barrier.
J Cell Biol. 2008, Nov 3;183(3); 409-17. IF: 9,598
Turowski P, Martinelli R, Crawford R, Wateridge D, Papageorgiou AP, Lampugnani MG, Gamp AC, Vestweber D, Adamson P, Dejana E, Greenwood J.
Phosphorylation of vascular endothelial cadherin controls lymphocyte emigration.
J Cell Sci. 2008, Jan 1;1211(Pt 1); 29-37. IF: 6,383
Dejana E, Orsenigo F, Lampugnani MG.
The role of adherens junctions and VE-cadherin in the control of vascular permeability.
J Cell Sci. 2008, Jul 1;121(Pt 13); 2115-22. IF: 6,383
D'Alessio S, Gerasi L, Blasi F.
uPAR-deficient mouse keratinocytes fail to produce EGFR-dependent laminin-5, affecting migration in vivo and in vitro.
J Cell Sci. 2008, Dec 1;121(Pt 23); 3922-32. IF: 6,383
Malacrida S, Agata S, Callegaro M, Casella C, Barana D, Scaini MC, Manoukian S, Oliani C, Radice P, Barile M, Menin C, D'Andrea E, Montagna M.
BRCA1 p.Val1688del is a deleterious mutation that recurs in breast and ovarian cancer families from Northeast Italy.
J Clin Oncol. 2008, Jan 1;26(1); 26-31. IF: 15,484
Di Nicolantonio F, Martini M, Molinari F, Sartore-Bianchi A, Arena S, Saletti P, De Dosso S, Mazzucchelli L, Frattini M, Siena S, Bardelli A.
Wild-type BRAF is required for response to panitumumab or cetuximab in metastatic colorectal cancer.
J Clin Oncol. 2008, Dec 10;26(35); 5705-12. IF: 15,484
Gregori D, Lusa L, Rosato R, Silvestri L.
Evaluating effectiveness of preoperative testing procedure: some notes on modelling strategies in multi-centre surveys.
J Eval Clin Pract. 2008, Feb;14(1); 11-8. IF: 1,570
Hömig-Hölzel C, Hojer C, Rastelli J, Casola S, Strobl LJ, Müller W, Quintanilla-Martinez L, Gewies A, Ruland J, Rajewsky K, Zimber-Strobl U.
Constitutive CD40 signaling in B cells selectively activates the noncanonical NF-kappaB pathway and promotes lymphomagenesis.
J Exp Med. 2008, Jun 9;205(6); 1317-29. IF: 15,612
Camporesi S, Boniolo G.
Fearing a non-existing Minotaur? The ethical challenges of research on cytoplasmic hybrid embryos.
J Med Ethics, 2008 Nov;34(11); 821-5. IF:1,103
Testa I, Parazzoli D, Barozzi S, Garrè M, Faretta M, Diaspro A.
Spatial control of pa-GFP photoactivation in living cells.
J Microsc. 2008, Apr;230(Pt 1); 48-60. NO IF.
Lusa L, Peissel B, Manoukian S, Marchesi E, Radice P, Pierotti MA, Gariboldi M.
Re: Molecular Basis for Estrogen Receptor {alpha} Deficiency in BRCA1-Linked Breast Cancer.
J Natl Cancer Inst. 2008, May 21;100(10); 752-3. IF: 15,678
Nebuloni M, Cinque P, Sidenius N, Ferri A, Lauri E, Omodeo-Zorini E, Zerbi P, Vago L.
Expression of the urokinase plasminogen activator receptor (uPAR) and its ligand (uPA) in brain tissues of human immunodeficiency virus patients with opportunistic cerebral diseases.
J Neurovirol. 2008, Dec 29; 1-9. IF: 1.943
Panfoli I, Musante L, Bachi A, Ravera S, Calzia D, Cattaneo A, Bruschi M, Bianchini P, Diaspro A, Morelli A, Pepe IM, Tacchetti C, Candiano G.
Proteomic Analysis of the Retinal Rod Outer Segment Disks.
J Proteome Res. 2008, Jul;7(7); 2654-69. IF: 5,675
Sabouri-Ghomi M, Ciliberto A, Kar S, Novak B, Tyson JJ.
Antagonism and bistability in protein interaction networks.
J Theor Biol. 2008, Jan 7;250(1); 209-18. IF: 2,323
Ferrario C, Lavagni P, Gariboldi M, Miranda C, Losa M, Cleris L, Formelli F, Pilotti S, Pierotti MA, Greco A.
Metallothionein 1G acts as an oncosupressor in papillary thyroid carcinoma.
Lab Invest. 2008, May; 88(5); 474-81. IF: 4,479
Galaup A, Germain S.
Blocking PlGF, a future in anti-angiogenic therapy?
Med Sci (Paris). 2008, May;24(5); 459-462. NO IF
Vintersten K, Testa G, Naumann R, Anastassiadis K, Stewart AF.
Bacterial artificial chromosome transgenesis through pronuclear injection of fertilized mouse oocytes.
Methods Mol Biol. 2008, 415:83; 100. NO IF
Gallus L, Ferrando S, Bottaro M, Diaspro A, Girosi L, Faimali M, Ramoino P, Tagliafierro G.
Presence and distribution of FMRFamide-like immunoreactivity in the cyprid of the barnacle Balanus amphitrite (Cirripedia, crustacea).
Microsc Res Tech. 2008, Oct 20;72(2); 101-109. IF: 1,644
Colombo M, Giarola M, Mariani L, Ripamonti CB, De Benedetti V, Sardella M, Losa M, Manoukian S, Peissel B, Pierotti MA, Pilotti S, Radice P.
Cyclin D1 expression analysis in familial breast cancers may discriminate BRCAX from BRCA2-linked cases.
Mod Pathol. 2008, Oct;21(10); 1262-70. IF: 4,286
Frittoli E, Palamidessi A, Pizzigoni A, Lanzetti L, Garrè M, Troglio F, Troilo A, Fukuda M, Di Fiore PP, Scita G, Confalonieri S.
The Primate-specific Protein TBC1D3 is Required for Optimal Macropinocytosis in a Novel ARF6 Dependent Pathway.
Mol Biol Cell. 2008, Apr;19(4); 1304-1316. IF: 6,028
Oriente F, Fernandez Diaz LC, Miele C, Iovino S, Mori S, Diaz VE, Troncone G, Cassese A, Formisano P, Blasi F, Beguinot F.
Prep1 deficiency induces protection from diabetes and increased insulin sensitivity through a p160-mediated mechanism.
Mol Cell Biol. 2008, Sep;28(18); 5634-45. IF: 6,420
Micali N, Ferrai C, Fernandez-Diaz LC, Blasi F, Crippa MP.
Prep1 directly regulates the intrinsic apoptotic pathway by controlling Bcl-XL levels.
Mol Cell Biol Epub 2008 Dec 22. IF: 6,420
Carvalho M, Pino MA, Karchin R, Beddor J, Godinho-Netto M, Mesquita RD, Rodarte RS, Vaz DC, Monteiro VA, Manoukian S, Colombo M, Ripamonti CB, Rosenquist R, Suthers G, Borg A, Radice P, Grist SA, Monteiro AN, Billack B.
Analysis of a set of missense, frameshift, and in-frame deletion variants of BRCA1.
Mutat Res (FUND MOL M) 2009, Jan 15;660(1-2); 1-11 (Epub 2008 Dec 22.) IF: 4,159
Taddei A, Giampietro C, Conti A, Orsenigo F, Breviario F, Pirazzoli V, Potente M, Daly C, Dimmeler S, Dejana E.
Endothelial adherens junctions control tight junctions by VE-cadherin-mediated upregulation of claudin-5.
Nat Cell Biol. 2008, Aug;10(8); 923-34. IF: 17,623
Branzei D, Foiani M.
Regulation of DNA repair throughout the cell cycle.
Nat Rev Mol Cell Biol. 2008, Apr;9(4); 297-308. IF: 31,921
Colaluca IN, Tosoni D, Nuciforo P, Senic-Matuglia F, Galimberti V, Viale G, Pece S, Di Fiore PP.
NUMB controls p53 tumour suppressor activity.
Nature. 2008, Jan 3;451(7174); 76-80. IF: 28,751
François M, Caprini A, Hosking B, Orsenigo F, Wilhelm D, Browne C, Paavonen K, Karnezis T, Shayan R, Downes M, Davidson T, Tutt D, Cheah KS, Stacker SA, Muscat GE, Achen MG, Dejana E, Koopman P.
Sox18 induces development of the lymphatic vasculature in mice.
Nature. 2008, Dec 4;456(7222); 643-7. IF: 28,751
Branzei D, Vanoli F, Foiani M.
SUMOylation regulates Rad18-mediated template switch.
Nature. 2008, Dec 18;456(7224); 915-20. IF: 28,751
d'Adda di Fagagna F.
Living on a break: cellular senescence as a DNA damage response.
Nature Reviews Cancer. 2008, Jul;8(7); 512-22. IF: 29,190
Zecchini S, Cavallaro U.
Neural Cell Adhesion Molecule in Cancer: Expression and Mechanisms.
Neurochem Res (Epub 2008 Mar 6) IF: 1,811
Mosca R, Schneider TR.
RAPIDO: a web server for the alignment of protein structures in the presence of conformational changes.
Nucleic Acids Res. 2008, Jul 1;36 (Web Server issue). IF: 6,954
Perotti D, Gamba B, Sardella M, Spreafico F, Terenziani M, Collini P, Pession A, Nantron M, Fossati-Bellani F, Radice P.
Functional inactivation of the WTX gene is not a frequent event in Wilms' tumors.
Oncogene. 2008, Jul 31;27(33); 4625-32. IF: 6,440
Vecchi M, Confalonieri S, Nuciforo P, Vigano MA, Capra M, Bianchi M, Nicosia D, Bianchi F, Galimberti V, Viale G, Palermo G, Riccardi A, Campanini R, Daidone MG, Pierotti MA, Pece S, Di Fiore PP.
Breast cancer metastases are molecularly distinct from their primary tumors.
Oncogene. 2008, Apr 3;27(15); 2148-58. IF: 6,440
Bleeker FE, Felicioni L, Buttitta F, Lamba S, Cardone L, Rodolfo M, Scarpa A, Leenstra S, Frattini M, Barbareschi M, Grammastro MD, Sciarrotta MG, Zanon C, Marchetti A, Bardelli A.
AKT1(E17K) in human solid tumours.
Oncogene (Epub 2008 May 26) IF: 6,44
Uccini S, Perotti D, Colarossi C, Stoppacciaro A, Sardella M, Mannarino O, Collini P, Casieri P, Cozzi D, Amoroso L, Spreafico F, Radice P, Dominici C.
Molecular evidence of the independent origin of multiple Wilms tumors in a case of WAGR syndrome.
Pediatr Blood Cancer. 2008, Sep;51(3); 344-8. IF: 2,164
Alberici P, Gaspar C, Franken P, Gorski MM, de Vries I, Scott RJ, Ristimäki A, Aaltonen LA, Fodde R
Smad4 haploinsufficiency: a matter of dosage.
Pathogenetics. 2008, Nov 3;1(1):2. NO IF
Terenziani M, Sardella M, Gamba B, Testi MA, Spreafico F, Ardissino G, Fedeli F, Fossati-Bellani F, Radice P, Perotti D.
A novel WT1 mutation in a 46,XY boy with congenital bilateral cryptorchidism, nystagmus and Wilms tumor.
Pediatr Nephrol. (Epub 2008 Dec 2.) IF: 1,375
Baldessari D, Mione M.
How to create the vascular tree? (Latest) help from the zebrafish.
Pharmacol Ther. 2008, May;118(2); 206-30. IF: 7,968
Gardini A, Cesaroni M, Luzi L, Okumura AJ, Biggs JR, Minardi SP, Venturini E, Zhang DE, Pelicci PG, Alcalay M.
AML1/ETO oncoprotein is directed to AML1 binding regions and co-localizes with AML1 and HEB on its targets.
PLoS Genet. 2008, Nov;4(11); e1000275. IF: 8,721
Penkov D, Palazzolo M, Mondino A, Blasi F.
Cytosolic sequestration of Prep1 influences early stages of T cell development.
PLoS ONE. 2008, Jun 18;3(6); e2424. NO IF
Cortese K, Sahores M, Madsen CD, Tacchetti C, Blasi F.
Clathrin and LRP-1-independent constitutive endocytosis and recycling of uPAR.
PLoS ONE. 2008, 3(11); e3730. NO IF
Hayashi M, Raimondi A, O'Toole E, Paradise S, Collesi C, Cremona O, Ferguson SM, De Camilli P.
Cell- and stimulus-dependent heterogeneity of synaptic vesicle endocytic recycling mechanisms revealed by studies of dynamin 1-null neurons.
Proc Natl Acad Sci U S A. 2008, Feb 12;105(6); 2175-80. IF: 9,598
Di Nicolantonio F, Arena S, Gallicchio M, Zecchin D, Martini M, Flonta SE, Stella GM, Lamba S, Cancelliere C, Russo M, Geuna M, Appendino G, Fantozzi R, Medico E, Bardelli A.
Replacement of normal with mutant alleles in the genome of normal human cells unveils mutation-specific drug responses.
Proc Natl Acad Sci U S A. 2008, Dec 30;105(52); 20864-9. IF: 9,598
Lorusso L, Boniolo G.
Clustering humans: on biological boundaries.
Stud Hist Philos Biol Biomed Sci. 2008, Mar;39(1); 163-70. NO IF
Pia Ragno and Francesco Blasi
uPAR and proteases in mobilization of hematopoietic stem cells.
The Cancer Degradome (Wiley) Eds. 2008 P. 433-450. NO IF
Vicidomini G, Gagliani MC, Canfora M, Cortese K, Frosi F, Santangelo C, Di Fiore PP, Boccacci P, Diaspro A, Tacchetti C.
High Data Output and Automated 3D Correlative Light-Electron Microscopy Method.
Traffic. 2008, Nov;9(11); 1828-38. IF: 6,533
Lanzetti L, Di Fiore PP.
Endocytosis and Cancer: an 'Insider' Network with Dangerous Liaisons.
Traffic (Epub 2008 Aug 14) . IF: 6,533
Scita G, Confalonieri S, Lappalainen P, Suetsugu S.
RSp53: crossing the road of membrane and actin dynamics in the formation of membrane protrusions.
Trends Cell Biol. 2008, Feb;18(2) 52-60. IF: 13,527
Rambaldi D, Giorgi FM, Capuani F, Ciliberto A, Ciccarelli FD.
Low duplicability and network fragility of cancer genes.
Trends Genet. 2008, Sep;24(9); 427-30. IF: 9,729
Cheng KC; Members of the Zebrafish Community (M.Mione)
Views on four key questions about zebrafish research.
Zebrafish. 2008, Spring;5(1); 9-24. NO IF